老年人肌少症与心血管疾病共病研究进展

Progress in research of comorbidity of sarcopenia and cardiovascular diseases in the elderly

摘要:

随着人口老龄化到来,衰老相关性疾病已成为困扰各国政府的一个难题。心血管疾病作为代表性疾病,发病率逐年攀升。运动是心血管疾病防治的重要手段。老年人群运动能力及运动量的减低与心血管事件发生存在相关性。肌少症是一种以肌肉含量减少和(或)功能减退为表现的疾病,其与心血管疾病之间关系紧密。本文拟总结近年肌少症与心血管疾病的研究,从疾病的病理生理、相互作用、潜在机制、临床表现及诊断标准、治疗等多层面进行介绍,使上述疾病得到更为深入的理解。

Abstract:

With population aging, age-related diseases have posed a great challenge for governments around the world. Typically age-related cardiovascular diseases increases year by year. Exercise is an important approach to the prevention of and rehabilitation from cardiovascular diseases, and the reduced exercise capacity and quantity are associated with their incidence in the elderly population. Sarcopenia, characterized by reduced muscle mass and/or reduced function, is closely related to cardiovascular diseases. This review summarizes the recent studies focusing on sarcopenia and cardiovascular diseases in the respects of pathophysiology, interaction, potential mechanism, clinical manifestation diagnostic criteria and treatment with a view of providing a clear insight into those diseases.