血管炎生物制剂的研究进展

Progress in research of biological agents for vasculitis

摘要:

血管炎的具体病种很多、病情复杂。有相当数量的血管炎患者在接受常规治疗后会出现病情的加重或反复。近些年,生物制剂单用或与其他药物联用在治疗难治性血管炎和控制血管炎复发方面发挥了一定的优势。2012年欧洲抗风湿病联盟将血管炎分为7类,本文主要对近几年治疗这7类血管炎的生物制剂的研究进展作一综述,希望能为临床医师提供参考。

Abstract:

Vasculitis features in many diseases, making it a complex condition. Aggravation or recurrence is seen in a considerable number of patients receiving conventional treatment of vasculitis. In recent years, biologic agents alone or in combination with other drugs have shown some advantages in treating refractory vasculitis and controlling the recurrence of vasculitis. In 2012, the European League against Rheumatism classified vasculitis into 7 categories. This article mainly reviews the progress in biological agents for the treatment of these 7 categories of vasculitis in recent years with a view to providing reference for clinicians.