常见抗肿瘤药心脏毒性研究进展

Research progress of cardiotoxicity in common antineoplastic drugs

摘要:

随着肿瘤患者生存期延长,抗肿瘤药引起的心血管不良事件发生率明显升高,早期识别抗肿瘤药的心脏毒性对提高患者生存质量和改善预后有重要意义。为此,本文对临床常用抗肿瘤药心脏毒性的表现、机制、风险评估、监测和防治研究进展进行综述,以期早期发现和防治抗肿瘤药的心脏毒性。

Abstract:

With the prolongation of the survival time in cancer patients, the incidence of cardiovascular adverse events caused by antineoplastic drugs is increased significantly. Early identification of cardiotoxicity of these drugs is of great significance to improve the quality of life and prognosis. Therefore, this paper reviews the research progress on the manifestations, mechanism, risk assessment, monitoring and prevention of cardiotoxicity of commonly used antineoplastic drugs in clinical practice, with a view to early detection and prevention.