老年肺癌患者医院获得性肺炎临床分析

Clinical analysis on hospital-acquired pneumonia in the elderly with lung cancer

摘要:

目的 总结和分析老年肺癌患者并发医院获得性肺炎(HAP)的相关影响因素,从而采取相关预防措施,以改善老年肺癌患者HAP的预后。方法 回顾性地分析2013年2月至2016年7月北京老年医院215例老年肺癌住院患者的临床资料,单因素分析HAP相关的危险因素。结果 单因素分析结果表明,男性、卡氏评分(KPS)<7.0、TNM分期、侵入性操作、合并糖尿病和慢性阻塞性肺疾病(COPD)、住院时间长是老年肺癌患者合并HAP的危险因素。病原菌以革兰阴性菌为主,常伴有真菌感染。结论 晚期肺癌患者合并HAP是多因素综合作用的结果,应引起临床重视,根据痰培养结果及时控制感染,是提高晚期肺癌老年患者治疗效果的关键。

Abstract:

Objective To summarize and analyze the related factors of hospital acquired pneumonia (HAP) in the elderly patients with lung cancer, and to take relevant preventive measures to improve the prognosis of the disease. Methods Retrospective analysis was carried out on 215 elderly inpatients with lung cancer in our hospital from February 2013 to July 2016. Their clinical data were collected, and univariate analysis was adapted to explore the risk factors for HAP. Results Univariate analysis revealed that male, Karnofsky performance store (KPS)<7.0, tumor node metastasis (TNM) stage, invasive operation, complication of diabetes mellitus and chronic obstructive pulmonary disease, and length of hospital stay were the risk factors for HAP in the elderly with lung cancer. Gram-negative bacteria were the main pathogens, and the infections were usually associated with fungal infection. Conclusion HAP usually results from multiple factors in the elderly with advanced lung cancer. More attention should be paid to the patients. According to the results of sputum culture, timely controlling infection is the key to improve the curative effect of them.