离休干部237例体质量指数与全因死亡的分析研究

Analysis on body mass index and all-cause mortality in 237 retired military cadres

摘要:

目的 分析第二军医大学离休干部体质量指数（BMI）与全因死亡的关系。方法 收集2000年1月至2013年10月于长海医院老年病科住院的我校离休干部共237例的临床资料，并进行随访，随访截止时间为2014年10月31日。根据BMI分为4组：低体质量组，BMI＜20kg/m2；理想体质量组，BMI 20～24.9 kg/m2；超重组，BMI 25～27.9 kg/m2；肥胖组，BMI≥28kg/m2。采用Cox回归方法分析各组的全因死亡风险。结果 中位随访时间59个月，均无失访，随访结束时发生全因死亡115例。Cox回归分析不同BMI分组的全因死亡风险，校正混杂因素后，相对于低体质量组，理想体质量组、超重组和肥胖组的全因死亡风险分别下降53.6%（HR＝0.464，95%CI：0.239～0.901，P＜0.05）、65.2%（HR＝0.348，95%CI：0.162～0.749，P＜0.05）、74.2%（HR＝0.258，95%CI：0.103～0.644，P＜0.05)。结论 随着BMI增加，离休干部全因死亡风险呈下降趋势。

Abstract:

Objective To analyze the correlation between body mass index (BMI) and all-cause mortality in the retired military cadres from the Second Military Medical University. Methods Clinical data of 237 retired military cadres hospitalized in our department from January 2000 to October 2013 were collected, and they were followed up until October 31, 2014. They were divided into 4 groups according to their BMI, that is, low body mass group (BMI＜20kg/m2), ideal body mass group (BMI 20.0?24.9kg/m2), overweight group (BMI 25.0?27.9kg/m2) and obesity group (BMI ≥28kg/m2). Cox regression analysis was used to investigate the all-cause mortality risks in the groups. Results The cohort of retired cadres were followed up for a median duration of 59 months, and no one was lost. All-cause mortality was 115 subjects when the follow-up ended. Cox regression analysis indicated that the all-cause mortality was decreased by 53.6% in ideal body mass group (HR＝0.464, 95%CI: 0.239?0.901, P＜0.05), 65.2% in overweight group (HR＝0.348, 95%CI: 0.162?0.749, P＜0.05) and 74.2% in obesity group (HR＝0.258, 95%CI: 0.103?0.644, P＜0.05) when compared with low body mass group after adjustments for confounders. Conclusion The increase of BMI is associated with the decreased risk of all-cause death in the retired military cadres.