老年男性前列腺体积与代谢因素的关系研究

Relationship of prostate volume with metabolic factors in older men

摘要:

目的 探讨健康体检老年男性前列腺体积（PV）与代谢因素的关系。方法 自2010年5月至2011年7月收集在海南医学院附属医院体检、相关数据完整的132名老年男性体检者的资料。年龄60～89（71.00±8.96）岁。记录其年龄、身高、体质量、血压。体质量指数（BMI）由体质量/身高2计算得出。腹部彩超测得前列腺三径（纵径、横径、及前后径, 并用公式“纵径×横径×前后径×0.52”计算PV）。检测并记录空腹血糖（FPG）、糖化血红蛋白（HbA1c），总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C），血尿酸（SUA）等。采用SPSS16.0统计软件进行数据分析。结果 年龄、收缩压（SBP）与PV呈正相关关系（P＜0.05）；BMI、舒张压、 LDL-C、HbA1c、FPG及SUA与PV无明显相关关系（P＞0.05）。结论 SBP及年龄是老年良性前列腺增生症的危险因素；而BMI、舒张压、LDL-C、HbA1c、FPG和SUA等因素与老年PV无明显相关关系。

Abstract:

Objective To investigate the relationship of prostate volume (PV) with metabolic factors in healthy older men. Methods A total of 132 older men with whole clinical data of health examination from the Health Check-up Center in our hospital from May 2010 to July 2011 were recruited in this study. Their age ranged from 60 to 89 (71.00±8.96) years. The data, including age, height, body mass and blood pressure were recorded, and body mass index (BMI) was calculated. Three positions of PV were measured through abdominal ultra-sound imaging, and PV was calculated in the formula of transverse diameter×longitudinal diameter×anteroposterior diameter×0.52. Fasting plasma glucose (FPG), glycosylated hemoglobin A1c (HbA1c), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and serum uric acid (SUA) were measured. Statistical analysis was performed using SPSS for Windows version 16. Results Age and systolic blood pressure (SBP) were positively correlated with PV (P＜0.05), but BMI, diastolic blood pressure (DBP), and the levels of LDL-C, HbA1c, FPG and SUA had no obvious association with PV (P＞0.05). Conclusion SBP and age are risk factors for benign prostatic hyperplasia in aged men, but BMI, DBP, LDL-C, HbA1c, FPG and SUA are not related to PV in our cohort.