老年临终患者并发贫血相关因素分析

Relevant factors for anemia in elderly hospice inpatients: an analysis of 310 cases

摘要:

目的 探讨老年临终患者并发贫血的相关因素，以利于合理防治。方法 回顾性地调查北京老年医院内科临终住院患者的临床资料，对86例并发贫血病例（试验组）与224例未并发贫血病例（对照组）进行比较分析。结果 多因素logistic逐步回归分析显示：恶性肿瘤[相对危险度（OR）：4.936；95%可信区间（CI）：1.769～13.769 ]、心脑疾病（OR：3.445；95%CI：1.267～9.368）、抗生素的应用（OR：3.433；95%CI：2.049～5.752）、低蛋白血症（OR：3.385；95%CI：1.378～8.315）、糖尿病（OR：3.064；95%CI：1.233～7.611）、年龄（OR：1.172；95%CI：1.105～1.244）、住院时间（OR：1.033；95%CI：1.021～1.045）、营养支持方法（OR：0.488；95%CI：0.267～0.892）是老年临终患者并发贫血的相关因素。结论 贫血是老年临终患者的常见并发症，恶性肿瘤、低蛋白血症、住院时间长、年龄较大以及伴有慢性基础病（心脑疾病、糖尿病）是老年临终患者并发贫血的危险因素。加强营养支持治疗，可预防老年临终患者贫血发生。

Abstract:

Objective To investigate the relevant factors for anemia in elderly hospice inpatients in order to facilitate better preventation and control. Methods Clinical data of the hospice inpatients from Department of Internal Medicine in our hospital from May 2010 to December 2012 were collected in this study. A retrospective investigation was carried out on the 86 cases with anemia (experimental group) and 224 cases without anemia (control group). Results Multivariate logistic stepwise regression analysis showed that malignant tumors [odds ratio (OR)＝4.936; 95% confidence interval (CI)＝1.769 to 13.769), cardio-cerebral diseases (OR＝3.445; 95%CI＝1.267 to 9.368), antibiotic use (OR＝3.433; 95%CI＝2.049 to 5.752), hypoalbuminemia (OR＝3.385; 95%CI＝1.378 to 8.315), diabetes mellitus (OR＝3.064; 95%CI＝1.233 to 7.611), age (OR＝1.172; 95%CI＝1.105 to 1.244), length of stay in hospital (OR＝1.033; 95%CI＝1.021 to 1.045), nutrition support method (OR＝0.488; 95%CI＝0.267 to 0.892) were significant for anemia in elderly hospice inpatients (P＜0.05). Conclusions Anemia is quite common in the elderly hospice inpatients. Malignant tumor, hypoalbuminemia, prolonged hospitalization, senior age, and chronic comorbidity (cardio-cerebral diseases and/or diabetes mellitus) are risk factors for occurrence of anemia. Strengthening nutrition support will be helpful for elderly hospice inpatients to prevent anemia.