持续气道内正压通气治疗阻塞性睡眠呼吸暂停低通气综合征合并缺血性心脏病的研究进展

Continuous positive airway pressure in treatment of obstructive sleep apnea-hypopnea syndrome with coexisting ischemic heart disease: a research progress

摘要:

无创气道正压通气治疗是成人阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的首选治疗方案，以持续气道内正压通气（CPAP）最为常用。临床中发现部分缺血性心脏病患者合并有不同程度的OSAHS，使用无创呼吸机治疗后，心脏功能明显改善，同时心脏结构也发生部分可逆性改变，OSAHS与缺血性心脏病的相关性可望成为一个值得探讨的问题。为进一步加强呼吸内科医师和心内科医师对该病的认识，本文就CPAP在OSAHS与缺血性心脏病中的诊治进展作一综述。

Abstract:

Non-invasive positive pressure ventilation (NIPPV) is the most preferred treatment modality for adult patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Among all types of NIPPV, continuous positive airway pressure (CPAP) is the most popular one. Clinical trials have demonstrated that quite a few ischemic heart diseases (IHD) patients had OSAHS coexisted simultaneously, and these patients showed significant improvement in cardiac function after CPAP treatment. Besides, their cardiac structure displayed partial reversible changes. These findings made the association between OSAHS and IHD be a hot topic worthy of our thorough investigation. In order to further strengthen the understanding of this condition in respiratory physicians and cardiologists, we reviewed the progress in CPAP in the diagnosis and treatment of IHD patients with coexisting OSAHS.