老年住院患者97例死亡病因分析及其超敏C-反应蛋白与血脂变化回顾

Causes of death and serum levels of high-sensitivity C-reactive protein and lipids: a retrospective study on 97 elderly hospitalized patients

摘要:

目的 探讨老年死亡患者一般情况和疾病分布，分析血清超敏C-反应蛋白（hs-CRP）、血脂在死因第一诊断为冠心病（CHD）的死亡患者中的变化规律。方法 收集整理老年科住院死亡病例97份进行统计分析，并对死因第一诊断为CHD和非CHD患者的hs-CRP、血脂进行回顾对比分析。结果 分析提示总病死率0.89%，男性病死率1.12%，女性病死率0.69%，前者高于后者（P＜0.05）；前5位死亡疾病是：急性心肌梗死、慢性充血性心脏病、肺部感染、心源性猝死、多个心脏瓣膜病；CHD死亡患者的总胆固醇（TC）含量高于非CHD死亡患者（P＜0.05），hs-CRP、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）水平差异无统计学意义（P＞0.05）。结论 CHD是老年科患者死亡的最主要原因，CHD老年死亡患者的胆固醇较非CHD死亡患者高。

Abstract:

Objective To investigate the general condition and distribution of diseases in the death of the elderly patients, and analyze the change profile of serum high-sensitivity C-reactive protein(hs-CRP) and blood lipids in the patients died of coronary heart disease (CHD). Methods Clinical data of 97 died patients hospitalized in our department from 2009 to 2012 were collected and retrospectively analyzed. The patients were divided into 2 groups according to their causes of death being CHD or not. Their serum levels of hs-CRP and lipids were analyzed. Results The total mortality in our department at that period was 0.89%, with 1.12% for males, significantly higher than that for the females (0.69%, P＜0.05). The top 5 diseases of death cause were acute myocardial infarction, chronic congestion heart disease, pulmonary infection, sudden cardiac death and multiple valvular heart diseases. The serum level of total cholesterol (TC) was significantly higher in CHD-caused death group than in non-CHD one (P＜0.05). But there was no significant difference in the levels of hs-CRP, triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) between the 2 groups (P＞0.05). Conclusion CHD is the major cause of death in the elderly people. TC level is obviously higher in the elderly died patients with CHD than those without the disease.