消化系癌症并发抑郁症发病情况及相关因素分析

Incidence and related factors of depression in patients with digestive cancer

摘要:

目的 了解消化系癌症（DC）患者抑郁症发病情况并探讨其相关因素。方法 收集2008年6月至2011年3月两所三级甲等医院多个科室的DC患者321例，进行抑郁自评量表（SDS）和Hamilton抑郁量表（HAMD）的评定及抑郁相关因素调查，收回有效问卷315份，研究DC并发抑郁症的发病情况，进行相关因素分析。结果 DC患者抑郁发生率为44.76%，以轻、中度程度为主，与文化程度和TNM分期有关。结论 DC患者抑郁发生率较高，与文化程度和TNM分期相关，临床应加以辨识。

Abstract:

Objective To investigate the incidence and related factors of depression in patients with digestive cancer (DC). Methods A total of 321 (315 valid questionnaires) DC patients out of different departments in 2 tertiary hospitals from June 2008 to March 2011 were enrolled in this study. They were surveyed by Self-rating Depression Scale (SDS) and Hamilton Rating Scale for Depression (HAMD) to investigate the depression-related factors and the incidence of DC accompanied by depression. A correlation analysis was performed among the factors and incidence. Results The incidence of depression in patients with DC was 44.76%, mainly mild to moderate degree. The incidence was related with education levels and TNM stages. Conclusion The incidence of depression is quite high in patients with DC, and is correlated with education level and TNM stage. Special attention should be paid to the identification of depression in clinical practice.