振动反应成像在老年慢性阻塞性肺疾病患者疗效评估中的价值

Vibration response imaging in assessment of therapeutic efficiency of chronic obstructive pulmonary disease in the elderly

摘要:

目的 探讨振动反应成像（VRI）在老年慢性阻塞性肺疾病（COPD）患者疗效评估中的应用价值。方法 2012年1月至6月在南京医科大学附属南京医院（南京市第一医院）呼吸科住院的41例老年COPD急性加重期患者在治疗前后进行呼吸困难分级、动脉血气、肺功能和VRI检查。结果 治疗后患者的呼吸困难评分显著降低[（3.46±0.87） vs （2.17±0.80），P＜0.01]，动脉血气PaO2明显提高、肺功能改善。治疗后VRI图像明显改善，振动曲线异常评分由（3.61±1.09）降至[（2.85±1.26），P＜0.01]，动态图像异常评分由（10.54±2.91）降至[（6.15±2.23），P＜0.01]，肺部啰音数从（9.98±7.51）减少至[（3.15±4.44），P＜0.01]。结论 VRI可用于动态监测和评估老年COPD患者的疗效。

Abstract:

Objective To investigate the value of vibration response imaging (VRI) in the assessment and monitoring of therapeutic efficiency of chronic obstructive pulmonary disease (COPD) in the elderly patients. Methods A total of 41 patients (over 60 years old) with acute exacerbations of COPD hospitalized in our department from January to June 2012 were recruited in this study. Dyspnea score, arterial blood gases analysis, lung function test and VRI were performed on them before and after treatment. Results Dyspnea grade was significantly reduced after treatment [(3.46±0.87) vs (2.17±0.80), P＜0.01]. PaO2, lung function and VRI results were improved significantly after treatment. Dynamic image grades were reduced from (3.61±1.09) to (2.85±1.26) (P＜0.01), graph grades from (10.54±2.91) to (6.15±2.23) (P＜0.01), and crack counts from (9.98±7.51) to (3.15±4.44) (P＜0.01). Conclusion VRI is helpful in the assessment and monitoring of therapeutic efficiency of COPD in elderly patients.