Abstract:Music may play important role in life quality improvement, and also have effects on the change of heart rate and heart rate variability. Cheerful music significantly reduced the level of peri-operative patients’ anxiety, and the effect was even better than oral administration of midazolam. Thus, except for oral administration of midazolam for sedation, listening cheerful music, another higher effective way with less adverse effects, was used as the sedation before operation. Listening to music, as a proposed regimen, was also beneficial to patients who needed resting in bed after cardiac surgical procedure, who would receive interventional management, and who had been implanted the permanent cardiac pace maker. After resting in bed for 30 min, the level of cortisol was significantly lower in music group(484.4mmol/L) than in non-music group (618.8mmol/L, P＜0.05). Vocal and orchestral music cause much stronger correlations between cardiovascular or respiratory system in comparison with music in more uniform emphasis (P＜0.05). Classical music and meditation music exert greatest benefit on health. Particularly composed by Bach, Mozart or Italian composers, the music improves the quality of life effectively, and keeps physical and mental health.