Abstract:With the poplation aging, the prevalence of senile osteoporosis is gradually increased all over the world. Its main consequence, osteoporotic fractures, exerts greatly impact on individuals, families and society. High-risk populations for osteoporosis could be preliminarily screened out by using International Osteoporosis Foundation (IOF) one minute questionnaire of osteoporosis and osteoporosis self-assessment tool for Asia (OSTA) osteoporosis. The diagnosis of osteoporosis is based on a history of fragility fracture or results of bone mineral density determined by Dual energy X-ray absorptometry (DXA), and also need exclude secondary osteoporosis. Treatments include lifestyle adjustment, bone health supplements, and anti-osteoporosis medications. This article also compare the efficacy, safety and convenience of anti-osteoporosis drugs, and introduce new anti-osteoporosis drugs.