Abstract:Objective To evaluate the therapeutic effect for high risk benign prostatic hyperplasia (BPH) in the elderly. Methods Clinical data of 1065 high-risk BPH elderly patients with age over 70 years (ranging from 70 to 99 years, mean 80.44 years) who were admitted in our department during March 2002 to February 2012 were collected and retrospectively analyzed. All patients averagely had at least 4 complications, such as diabetes, hypertension, hyperlipidemia, cardiovascular events, and so on. The therapeutic safety and reliability of non-surgical treatment, bladder fistulization, transurethral and suprapubic prostatectomy were evaluated. Results Totally 352 cases received non-surgical treatment, but in whom catheterization induced urinary tract infection and life inconvenience though having no effect on the complications. Among the 102 cases undergoing bladder fistulization, no complication was aggravated but urinary tract infection occurred in all patients due to catheterization. In 326 cases treated with transurethral prostatectomy, 11 of them suffered from severe complications, and 2 died. A total of 85 cases were treated with suprapubic prostatectomy. There were 14 cases suffering from severe complications and 1 died. Conclusion Non-surgical and bladder fistulization are safe, but can not improve patients¢ life satisfaction. The prostatectomy is effective, but is susceptible to aggravated complications in high-risk elderly patients.