老年稳定性心绞痛患者用药及危险因素控制情况的分析

Drug usage and risk factors control in elderly patients with chronic stable angina

摘要:

目的 了解老年慢性稳定性心绞痛药物应用现状及危险因素控制情况。方法 于2010年6月1日至2010年12月1日期间对空军总医院门诊部冠心病患者进行调查，筛选资料完整的186例慢性稳定性心绞痛患者，对收集的数据进行统计分析。结果 调查中资料完整的186例老年慢性稳定性心绞痛患者中抗血小板药物、硝酸酯类、他汀类药物、β受体阻滞剂、血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂、钙离子拮抗剂药物使用率分别为87.1%(162/186)、84.9%（158/186）、68.8%（128/186）、54.8%（102/186）、50.0%（93/186）、48.4%（90/186），不同性别组间差异无统计学意义（P＞0.05）。患者低密度脂蛋白胆固醇控制达标率34.9%（65/186），合并高血压或慢性肾病者血压控制达标率58.3%(77/132)，合并糖尿病或糖耐量异常者糖化血红蛋白（HbA1c）控制达标率43.1%（25/58），血脂、血压及血糖达标率在不同性别组间差异无统计学意义（P ＞0.05）。结论 老年慢性稳定性心绞痛患者中各药物应用情况较指南要求尚有明显差距，各危险因素控制达标率仍亟待提高。

Abstract:

Objective To determine the drug usage and risk factors control in elderly patients with chronic stable angina. Methods From Jun 1, 2010 to Dec 1, 2010, patients with coronary artery disease in Outpatient Department of Air Force General Hospital were surveyed. Totally 186 elderly patients with chronic stable angina were screened out and their data were statistically analyzed. Results The usage rates of anti-plate drugs, nitrate, statins, beta-blockers, angiotensin-converting enzyme inhibitors/ angiotensin-receptor blockers and calcium channel blocker were 87.1% (162/186), 84.9% (158/186), 68.8% (128/186), 54.8% (102/186), 50.0% (93/186) and 48.4% (90/186) respectively. There was no significant difference in these drugs usage and risk factors control rate between the males and the females (P＞0.05). The qualification rate for low density lipoprotein cholesterol in the subjects was 34.9% (65/186). The qualification rate for blood pressure in patients with complicated hypertension or chronic renal diseases was 58.3% (77/132). The qualification rate for HbA1c in patients complicated with diabetes or impaired glucose tolerance was 43.1% (25/58). There was no statistical difference between males and females (P＞0.05). Conclusions The drugs usage in elderly patients with chronic stable angina has not met the standard according to the guideline on chronic stable angina yet. It is urgent to improve the risk factors control status for elderly patients with chronic stable angina.