Abstract:Resting heart rate is the quiet or inactive heart rate. When general condition is relatively stable, changes of heart rate directly reflect the functional state of heart and sympatheticus. Therefore, resting heart rate is not only involved in heart failure, acute myocardial infarction, hypertension and other cardiovascular diseases, but also has a direct causal relationship with cardiovascular events and death. Appropriate decrease of the heart rate by β-blockers can reduce the risk of cardiovascular death to some extent. For the elderly patients who cannot use β-blockers, ivabradine, which merely reduces heart rate, can improve not only myocardial remodeling and left ventricular systolic function, but also capillary density.