心脏再同步化治疗心力衰竭的研究进展

Advances in cardiac resynchronization therapy for heart failure

摘要:

药物能有效改善心力衰竭患者的症状，但是对于心功能III～IV级的严重心力衰竭患者, 心脏再同步化治疗是唯一能显著改善预后的有力治疗方法。本文从心脏再同步化治疗心力衰竭适应证的拓展、QRS时限与形态在CRT治疗中的重要地位、心脏再同步化治疗的优化程控与CRT治疗机制、CRT起搏电极植入技术及电极位置对应答效果的影响、CRT应答的预测因子评价与治疗展望五个方面对心脏再同步化治疗心力衰竭的研究进展进行综述。

Abstract:

Drugs can effectively improve the symptoms of heart failure. However, cardiac resynchronization therapy is the only effective way to get marked results for the severe heart failure patients with NYHA III-IV. This article reviewed the researches in five aspects: expansion of CRT indications in heart failure, the important roles of QRS duration and morphology in CRT treatment, optimization program regulation and mechanism in CRT, the effects of pole technology and position on response, the prediction factors of response and treatment advances in CRT.