睡眠呼吸暂停低通气综合征与心血管疾病相关性的临床分析

Clinical analysis of the relationship between sleep apnea-hypopnea syndrome and the morbidity of cardiovascular diseases

摘要:

目的临床观察不同程度睡眠呼吸暂停低通气综合征(SAHS)患者心血管病发生率及其两者的相关性,为引起心血管科医生对本病的重视提供临床依据.方法 63例疑似SAHS患者进行睡眠呼吸监测,依据多导睡眠图监测结果,分为正常、轻度、中度、重度睡眠呼吸暂停4组,根据临床表现、血液生化指标、心电图、心脏超声、动态血压及冠状动脉造影等检查诊断心血管疾病,分析不同程度睡眠呼吸暂停与心血管疾病发生率的相关性.结果体重指数与呼吸暂停低通气指数、呼吸紊乱指数显著正相关(r=0.355,0373,P＜0.05);中、重度SAHS组心血管病发生率明显高于正常及轻度SAHS组(P＜0.05或0.01).结论睡眠呼吸暂停的程度与心血管疾病的发生密切相关.

Abstract:

Objective To observe the morbidity of cardiovascular diseases in patients with sleep apnea-hypopnea syndrome, and to investigate the correlation between severity of sleep apnea and cardiovascular diseases.Methods Sixty-three patients suspected of SAHS wer