光学相干断层扫描技术在皮肤医学领域的应用进展

Application progress of optical coherence tomography in dermatology

【摘要】近年来,光学相干断层扫描(OCT)已被广泛应用于各种皮肤病研究,用于早期发现疾病及评估治疗效果。相较于传统病理诊断方法,OCT在检测速度、无创等方面具有极大优势,因此被越来越多的皮肤病学者重视,以挖掘其更大的应用价值。本文比较了OCT与皮肤病学中其他非侵入性成像技术的差异,并回顾了OCT系统的基本原理、分类及其在皮肤病学领域最新的应用进展。

基金项目:国家自然科学基金(82205294)；国家重点研发计划“中医药现代化研究”专项子课题(2019YFC1709305)；中央级公益性科研院所基本科研业务费专项资金(XTCX2021002)；中国中医科学院科技创新工程项目(CI2021A00601)

【Abstract】Optical coherence tomography (OCT) has been widely used for early detection and evaluation of therapeutic effects for various skin diseases in recent years. With dramatic advantages over traditional pathological diagnostic methods in detection speed and non-invasiveness, OCT has attracted more and more attention of dermatologists for broader applications. In this article, we compared the difference between OCT and other non-invasive imaging technologies applied in dermatology in vivo, and then reviewed the basic principles and classification of OCT systems and its recent applications progress in dermatology.

This work was supported by the National Natural Science Foundation of China (82205294), the Special Sub-Project on Modernization Research of Traditional Chinese Medicine of National Key Research and Development Program of China (2019YFC1709305), the Fundamental Research Funds for the Central Public Welfare Research Institutes (XTCX2021002) and the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences (CI2021A00601).