骨质疏松与肌少症之间的关系

Relationship between osteoporosis and sarcopenia

【摘要】骨质疏松和肌少症这两种慢性疾病有共同的危险因素和病理生理途径,均好发于老年人和绝经后的女性,且常常伴随出现,严重影响老年人的生活质量。因此,对骨质疏松和肌少症之间联系的探索,以及对两种疾病进行联合评估十分重要。本文将对骨骼与肌肉以及骨质疏松症与肌少症之间的关系进行综述,以期为临床骨骼肌肉疾病的诊断和治疗提供方向。

基金项目:国家重点研发计划(2021YFC2501703)；北京市医院管理中心临床医学发展专项经费(ZYLX202107)

【Abstract】Osteoporosis and sarcopenia, two chronic diseases with shared risk factors and pathophysiological pathways, are both common to the elderly and postmenopausal women and are often comorbid, seriously affecting the quality of life of the elderly. Therefore, it is very important to explore their relationship and to jointly evaluate the two diseases. This article reviews the relationship between the skeleton and muscles and between osteoporosis and sarcopenia to provide clinical orientation for the diagnosis and treatment of skeletomuscular diseases.

This work was supported by National Key Research and Development Program of China(2021YFC2501703) and Special Fund for Clinical Medicine Development of Beijing Hospital Administration Center (ZYLX202107).