老年下肢动脉硬化闭塞症相关危险因素分析及介入手术应用

Analysis of related risk factors and interventional treatment for lower extremity arteriosclerosis obliterans in the elderly

【摘要】下肢动脉硬化闭塞症(ASO)是最常见的外周血管疾病之一。ASO的危险因素包括年龄、性别、吸烟史、高血压、高血脂、冠心病以及高同型半胱氨酸血症等。尽管当前治疗手段(例如外科手术、血管腔内技术以及药物治疗等)不断进步,但ASO仍是造成截肢的一个主要原因。因此掌握老年ASO的相关危险因素并尽早预防是极为重要的。介入治疗具有创伤小、操作方便、术后恢复快、重复性强的优点,已成为目前临床上治疗ASO的首选措施。

基金项目:国家自然科学基金面上项目(81570424)

【Abstract】Lower extremity arteriosclerosis obliterans (ASO) is one of the most common peripheral vascular diseases. The risk factors for ASO include age, gender, smoking history, hypertension, hyperlipidemia, coronary heart disease, and hyperhomocysteinemia. Although some progresses have been made in current treatments such as surgical procedures, endovascular techniques, and drug therapy, ASO remains a major cause of amputations. Therefore, it is very important to master the related risk factors for ASO and prevent them as early as possible in the elderly patients. Interventional therapy has the advantages of small trauma, easy operation, quick recovery and good reproducibility, and has become the first choice for the treatment of lower extremity ASO.