经皮冠状动脉介入治疗对老年缺血性心肌病心功能和预后的影响

Percutaneous coronary intervention in treatment of heart failure derived from geriatric ischemic cardiomyopathy

【摘要】目的评价经皮冠状动脉介入治疗(PCI)对老年缺血性心肌病心功能不全的近期疗效及远期预后的影响。方法患者分为两组。一组行PCI加适当药物治疗;另一组单纯药物保守治疗。对比观察近期临床效果及长期随访以了解远期预后的不同。结果PCI组近期症状体征改善、左室射血分数提高,1年、2年因心功能不全及严重心肌缺血再次入院治疗人次及4年、8年随访心源性死亡率各方面与单纯药物治疗组有较显著差异。结论PCI在老年缺血性心肌病所致心功能不全的治疗方面具有积极意义,尤其对改善远期预后有一定价值。?更多还原

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【Abstract】Objective To investigate the effects of percutaneous coronary intervention(PCI) on the treatment and prognosis of heart failure derived from ischemic cardiomyopathy in aged patients. Methods The subjects were divided into 2 groups: treatment group(n=55)and control group(n=56).The patients in the treatment group received PCI as well as conservative medication,while the patients in the control group underwent conservative medication only. The short-term therapeutic effects and long-term prognosis were compared between the two groups. Results In PCI treatment group, the patients had a significant amelioration of physical signs, significant elevation of LVEF, significant reduction of rehospitalization frequency in 1-and 2-year follow-up visit,and cardiac death in 4-and 8-year follow-up visit.It was significantly different compared to the control group(P<0.05). Conclusion The application of PCI in treating heart failure resulting from ischemic cardiomyopathy in aged patients is feasible and fruitful if the patients can stand the procedure.Especially,the long-term prognosis is statisfactory.