衰弱对老年慢性肾脏病患者预后的影响

Impact of frailty on prognosis of chronic kidney disease in the elderly

摘要:

老年人是慢性肾脏病(CKD)的高危人群,老年CKD患者的预后受多种因素影响。衰弱是一种重要的老年综合征,老年CKD患者的衰弱患病率高于普通老年人群,衰弱可增加老年CKD患者心血管事件、全因死亡风险、急性肾损伤发生风险及加速肾功能进展,衰弱是不良健康结局的预测因子,早期有效识别衰弱并及时干预对改善老年CKD患者的预后有重要意义。

Abstract:

Chronic kidney disease (CKD) is an important health problem in the elderly, whose prognosis is affected by multiple factors. Frailty is an important geriatric syndrome prevalent in patients with CKD. Frailty is associated with an increased risk for all-cause death and cardiovascular disease, acute kidney injury and CKD progression. Frailty is a significant predictor of adverse health outcomes, and its early detection and timely interventions are of great significance in improving the prognosis of the elderly CKD patients.