周围性听觉障碍与阿尔茨海默病的关系

Association of peripheral hearing loss and Alzheimer′s disease

摘要:

周围性听觉障碍是好发于老年群体的感官障碍,阿尔茨海默病(AD)是患病率最高的神经系统变性疾病,研究发现周围性听觉障碍是AD发生的独立危险因素。目前两者相关的机制假说包括认知储备机制、社会隔离机制及共同病因机制。干预周围性听觉障碍可以延缓老年人认知功能减退,改善AD患者情绪及行为症状。

Abstract:

Peripheral hearing loss is quite prevalent in senior population, while Alzheimer′s disease (AD) is the most frequent neurodegenerative disease. Evidence showed that peripheral hearing loss is an independent risk factor of AD. The hypotheses regarding the mechanism of their relationship include cognitive reserve, social isolation and common etiology. Intervention of peripheral hearing loss attenuates the cognitive decline of senior population, and improves emotional and behavioral symptoms of AD patients.